Insight Veterinary Specialty Pathology is growing up! We have partnered with Specialty VETPATH to provide better, faster service to more clinics, their clients, and their patients! AND access to more specialty pathology disciplines - dermatopathology, oral/maxillofacial pathology, and more are available through this new "alliance". Still independent, still patient focused - just better! Whether a new clinic looking for more info or to submit a biopsy, or a current or past client looking to get up to date on new protocols, call 206-453-5691 or email email@example.com to get started! 2020 has been a mess - Insight VSP and SVP are trying to make specialized veterinary pathology a little better through it all! Click the SVP or Surgical Oral Pathology for Animals logos for excellent specialty pathology service. Be Safe, Be well, Be kind!
Glaucoma is relatively common in the dog, with a number of potential causes. Canine primary angle-closure glaucoma is a common such cause, with important prognostic and treatment indications for the remaining, fellow eye. Accurate diagnosis is, therefore, critical, and can be hindered by concurrent lesions like uveitis and preiridal membranes. While the pathogenesis of glaucoma development in this disease remains incompletely understood, the underlying lesion is goniodysgenesis (literally, malformed angle). The image to the right is a photomicrograph of a normal canine iridocorneal angle, with a perforated pectinate ligament (*).
In the image below, the asterisk denotes a thick and imperforate pectinate ligament - the lesion of goniodysgenesis. The ciliary cleft is open, and trabecular meshwork are visible, indicating a non-glaucomatous state at this point.
In this image, the thickened pectinate ligament (*) overlies a collapsed ciliary cleft
and inapparent trabecular meshwork (narrow rectangle), consistent with chronic
glaucoma. This dog's other eye is at high risk for primary angle-closure glaucoma.
Dr. Christopher Reilly